1 RHEUMATOID ARTHRITIS AND THE HAND Introduction Essential anatomy and physiology Essentialimmunology Pathology Aetiopathogenesis of theumatoid arthritis Treatment of theumatoid arthritis Prognosis 2 SOFT TISSUE RHEUMATIC DISEASE INVOLVING THE SHOULDER AND ELBOW Introduction Anatomy of the shoulder Pathophysiology of rotator cuff disease Clirucal aspects of shoulder pain Investigahons Treatment Rehabilitation and outcome Anatomy of the elbow Lateralepicondylitis 3 NERVE COMPRESSION SYNDROMES Introduchon Peripheral nerve anatomy Pathophysiology and classification of nerve injury Electrophysiology Carpal tunnel syndrome Treatment of carpal tunnel syndrome Cubital tunnel syndrome 4 BACK PAIN Introduction Normal lumbar spine anatomy Funchon of the lumbar spine Pain from the lumbar spine Epidemiology of low back pain Treatment of low back pain 5 BONE STRUCTURE AND FUNCTION IN NORMAL AND DISEASE STATES Introduction Normal skeletal structure and function Metabolic bone disease Osteoporosis: pathophysiology and risk factors Epidenuology of fractured hip Essential anatomy of the hip Surgical management of hip fractures Medical management of osteoporotic hip fracture 6 ARTICULAR CARTILAGE IN HEALTH AND DISEASE Introduction Anatomy Biochemistry Pathophysiology of osteoarthritis Clinical features of osteoarthritis Essential anatomy of the knee joint Epidemiology of osteoarthritis Management of osteoarthritis 7 CRYSTAL ARTHROPATHIES AND THE ANKLE Introduction Differential diagnosis of acute monarthritis of the ankle Essential anatomy Investigations and diagnosis Pathophysiology of gouty arthritis Treatment of acute gout Treatment of chronic gout Chondrocalcinosis Treatment of calcium crystal assoaated arthritis 8 DISORDERS OF SKELETAL MUSCLE Introduction Anatomy of skeletal muscle Investigations Muscle diseases Acquired muscle diseases Inherited muscle disorders Muscle disorders in which pain is the main feature Fibromyalgia 9 AUTOIMMUNITY AND THE MUSCULOSKELETAL SYSTEM Introduction Immunology Serological manifestations of autoimmunity Clinical features and epidemiology Pathology Aetiology Treatment Variants of SLE 10 TRAUMA AND THE MUSCULOSKELETAL SYSTEM Introduction Pathophysiology Functional anatomy of the knee joint Diagnosis of fracture Management of fractures 11 INFECTION AND THE MUSCULOSKELETAL SYSTEM Introduction General principles of musculoskeletal infection Host defences against infection Blood supply of bone Acute infection of bone and joints Antibiotic therapy Chronic infections of bones and joints Glossary Index