Chapter 1 General knowledge of animal experiments Section 1 Ethics and protection of experimental animals Section 2 General knowledge of animal experiments． Section 3 Introduction of common surgical instruments Section 4 Writing format and requirements of laboratory report Chapter 2 Experiments of pharmacological general principles Section 1 Determination of dose-response relationship of drug Section 2 Measurement of LD50 Section 3 Determination pA2 of diphenhydramine Section 4 Body distribution of ibuprofen Section 5 Determination of the serum concentration and pharmacokinetics of phenolsul fon phthalein Section 6 Measurement of half-life time of drug Section 7 Effects of liver function on drug action． Section 8 The effects of different routes of administration on drug action Chapter 3 Experiments of autonomic nervous system． Section 1 Effects of drugs on eye pupils Section 2 Effects of drugs on isolated intestinal smooth muscle． Section 3 Poisoning of organophosphates and rescue． Section 4 Effects of drugs on isolated aorta ring Section 5 Effects of drugs on blood pressure in anesthetized animals Section 6 Effects of drugs on hemodynamics in anesthetized animals Chapter 4 Experiments of central nervous system Section 1 Sedative-hypnotic effects of diazepam Experiment 1 Effects of diazepam on spontaneous activity Experiment 2 Hypnotic effects of diazepam Section 2 Influence of enzyme inducer and inhibitor on pentobarbital-induced hypnotic effects Section 3 Anticonvulsant effect of phenobarbital Experiment 1 Maximal electroshock test Experiment 2 Chemical-induced convulsion Section 4 Analgesic effect of drugs Experiment 1 Analgesic effect of aspirin by writhing test Experiment 2 Analgesic effect of pethidine by hot plate test Section 5 Effects of chlorpromazine on body temperature regulation Section 6 Conduction anesthetic effect of procaine Section 7 Comparison of anesthetic effect and toxicity of local anesthetics Experiment 1 Local anesthetic action of procaine Experiment 2 Comparison of toxicity of local anesthetics Section 8 Effects of vasoconstrictor and vasodilator on local anesthesia duration Chapter 5 Experiments of cardiovascular system Section 1 Effects of ions and drugs on isolated heart Section 2 Anti-arrhythmic effects of drugs Experiment 1 Effects of lidocaine on BaC12 induced arrhythmias Experiment 2 Effects of quinidine on aconitine induced arrhythmias Experiment 3 Effect of propranolol on adrenaline induced tachycardia Section 3 Effects of cardiac glycosides on failed heart Section 4 Effects of drugs on acute ischemic ECG appearance induced by pituitrin Section 5 Anti-hypoxia effects of anti-anginal drugs Chapter 6 Experiments of internal organs system Section I Anti-coagulant effect of heparin Section 2 Effects of furosemide on urine volume and electrolytes Section 3 Effects of drugs on asthma stimulated by histamine Section 4 Effects of chlorphenamine on histamine increased capillary permeability Section 5 Effects of drugs on bile secretion Chapter 7 Experiments of endocrine system Section 1 Anti-inflammatory effects of glucocorticoids Section 2 Effects of insulin and oral anti-diabetes drugs on blood glucose levels Section 3 Hypoglycemic response to insulin overdose and rescue Section 4 Effects of indomethacin on gout attack Section 5 Effects of drugs on isolated uterine contraction Chapter 8 Medical experiment research training Section 1 Basic knowledge and skills of medical literature retrieval Section 2 Selection of topics Section 3 Experimental design Section 4 Implementation of experimental research Section 5 Writing of research paper Appendix Appendix 1 Physiological parameters of commonly used laboratory animals Appendix 2 Preparation of common physiological solutions Appendix 3 Dosage conversion of different experimental animals Index of English-Chinese terms
鄂公網(wǎng)安備 42010302001612號(hào) 