王勇，江蘇大學(xué)食品與生物工程學(xué)院，副教授，王勇，江蘇大學(xué)食品與生物工程學(xué)院，副教授。1985年畢業(yè)于復(fù)旦大學(xué)生物系，獲理學(xué)學(xué)士學(xué)位；2003年畢業(yè)于江蘇大學(xué)生命科學(xué)研究院，獲工學(xué)博士學(xué)位。1985-1997年就職于中國(guó)農(nóng)業(yè)科學(xué)院蠶業(yè)研究所（鎮(zhèn)江），1994-1996年主持完成了國(guó)家自然科學(xué)基金“人工合成肽基因?qū)肷?shù)的研究”課題；1997-2001年就職于中美合作上海實(shí)宏紙業(yè)有限公司；2001年以后在江蘇大學(xué)任教，講授碩士研究生《分子生物學(xué)》雙語(yǔ)課程，本科《分子生物學(xué)》雙語(yǔ)課程，本科《生物信息學(xué)》雙語(yǔ)課程。2006年與美國(guó)學(xué)者Sylvain W. Lapan先生合作完成《英漢對(duì)照分子生物學(xué)導(dǎo)論》講義稿，用于2006~2007年本科教學(xué)總結(jié)、完善后，于2008年送交化學(xué)工業(yè)出版社正式出版。 所獲獎(jiǎng)項(xiàng)：江蘇大學(xué)2015年度本科教學(xué)先進(jìn)個(gè)人、“分子生物學(xué)雙語(yǔ)課程建設(shè)與實(shí)踐”獲江蘇大學(xué)高等教育教學(xué)成果一等獎(jiǎng)（2009年）、“分子生物學(xué)雙語(yǔ)教學(xué)實(shí)踐與探索”獲全國(guó)首屆生物化學(xué)與分子生物學(xué)教學(xué)研討會(huì)論文三等獎(jiǎng)（2007年）。
圖書(shū)目錄
Introduction Chapter 1 Amino Acids to Proteins 1.1Protein Composition 1.2Protein Conformations 1.2.1Describing Protein Structure 1.2.2Chemical and Physical Basis for Protein Folding 1.3Protein Structure and Function:A Few Examples 1.4The Dynamics of Proteins 1.5Experiments Summary Vocabulary Review Questions Exploration Questions
Chapter 2 Nucleic Acids 2.1Properties of a Genetic Material 2.2Nucleic Acids and DNA structure 2.2.1Nucleotides 2.2.2General Structure of Nucleic Acids 2.2.3Structure of DNA 2.3DNA as the Genetic Material 2.4DNA in the Cell 2.5RNA (Ribonucleic Acid) 2.6Experiments Summary Vocabulary Review Questions Exploration Questions
Chapter 3 Transcription in Prokaryotes:Mechanism and Regulation 3.1Why Use an RNA Intermediate 3.2Mechanism of Transcription 3.2.1Promoters 3.2.2RNA Polymerase 3.2.3Transcription Mechanism in Three Phases 3.3Regulation of Gene Expression in Prokaryotes 3.3.1Coordinate Regulation 3.3.2The Lac Operon 3.3.3The Trp Operon 3.3.4Ara and Gal Operons 3.4Experiments Summary Vocabulary Review Questions Exploration Questions
Chapter 4 Transcription in Eukaryotes:Mechanism and Regulation 4.1Eukaryotic RNA Polymerases 4.2Eukaryotic Promoters 4.3General Transcription Factors and Initiation 4.3.1TFⅡD 4.3.2Other TFⅡs 4.3.3General Transcription Factors for RNA Polymerase Ⅰand Ⅲ 4.4Specific Transcription Factors and Transcriptional Regulation 4.4.1Activators 4.4.2Repressors 4.4.3Enhancers and Silencers 4.5Structures of Specific Transcription Factors 4.5.1DNA-Binding Motifs in Prokaryotes 4.5.2DNA-Binding Motifs in Eukaryotes 4.6Experiments 4.6.1RNA Polymerase Targets 4.6.2Modularity of Specific Transcription Factors Vocabulary Review Questions Exploration Questions
Chapter 6 Translation 6.1The Genetic Code 6.2Mechanism of Translation in Prokaryotes 6.2.1Initiation 6.2.2Elongation 6.2.3Termination 6.3Translation in Eukaryotes 6.4tRNA Structure and Wobble 6.4.1Anti-codons 6.4.2Wobble 6.5Experiments 6.5.1Deciphering the Genetic Code 6.5.2Direction of Translation Summary Vocabulary Review Questions Exploration Questions
Chapter 7 Regulation of Gene Expression in Eukaryotes 7.1Histones and Transcriptional Regulation 7.1.1Histones and DNA Organization 7.1.2Histones and Transcription 7.1.3Covalent Modification of Histones 7.1.4Proteins that Recognize and Modify Histones 7.2Post-Transcriptional Regulation 7.3Nuclear Export 7.4RNA Stability 7.4.1mRNA Stability Regulation by Proteins 7.4.2mRNA Stability Regulation by Small RNAs 7.5Translational Control 7.5.1Global Control 7.5.2mRNA-Specific Control 7.6mRNA Localization 7.7Protein Regulation 7.8Experiments 7.8.1Beads-on-a-string Structure 7.8.2Repression of Gene Expression in Heterochromatin Summary Vocabulary Review Questions Exploration Questions
Chapter 8 DNA Replication 8.1Semi-Conservative Replication 8.2Initiation of Replication 8.3Semi-Discontinuous Replication 8.4Elongation of Replication and its Proteins 8.4.1Helicase and SSBs 8.4.2DNA Polymerases 8.4.3Explanation for 3′→5′Synthesis 8.4.4Primers 8.5DNA Topology 8.6DNA Replication in Eukaryotes 8.6.1Initiation of DNA Replication in Eukaryotes 8.6.2Telomeres 8.7Experiments Summary Vocabulary Review Questions Exploration Questions
Chapter 9 Mutations and Mutation Repair 9.1DNA Damage and Mutations 9.2Point Mutations 9.2.1Mismatched Base 9.2.2Spontaneous Mutations 9.2.3Induced Mutations 9.3Insertions and Deletions 9.3.1Strand Slippage 9.3.2Transposons 9.3.3Intercalating Agents 9.4Large-Scale DNA Changes 9.5Consequences of DNA Mutations 9.5.1Consequences of Point Mutations 9.5.2Consequences of Insertions and Deletions 9.5.3Consequences of Translocations 9.5.4Mutation Hot Spots 9.6Mutation Repair 9.6.1Direct Reversal 9.6.2Mismatch Repair 9.6.3Nucleotide Excision Repair 9.6.4Base Excision Repair 9.6.5Double-Stranded Break Repair 9.7Experiments 9.7.1Nucleotide Excision Repair and Human Disease 9.7.2The Ames Test Summary Vocabulary Review Questions Exploration Questions
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