Section 1 Principles of Drug Therapy Chapter 1 Introduction to Pharmacology The Aim of Pharmacology The History of Pharmacology Change of Drug Discovery Strategy Processes of Drug Discovery Preclinical Pharmacology Research (Non-clinical Research) Clinical Trial Chapter 2 Pharmacokinetics Process of Drug in Body Process for Drug Transport across Membranes and Drug Transporters Drug Absorption and Routes of Administration Drug Distribution and Binding to Plasma Protein Drug Metabolism Drug Elimination Kinetic Process of Drug in Body Principles of Pharmacokinetics Pharmacokinetic Parameters and Basic Calculation Equations Chapter 3 Pharmacodynamics Specific Mechanisms of Drug Action Drug-receptor Interactions Effects on，Enzymes Effects on Transporters Effects on Structural and Functional Proteins Effects on Genes Common Note Concerning the Drug Mechanism Non-specific Mechanisms of Drug Action Dose-response Relationships Dose-response Relationship Curves Relation between Dose-response Variation in Drug Responsiveness Sources of Inter-individual Variation of Drug Response Section 2 Drugs Affecting the Autonomic Nervous System Chapter 4 Introduction Anatomy arid General Functions of Efferent Nervous System Autonomic Nervous System Somatic Motor Nerves Neurotransmitters in the Efferent Nervous System Acetylcholine Norepinephrine Receptors in the Efferent Nervous System Cholincceptors Adrenoceptors Dopamine Receptors Drugs Affecting the Autonomic Nervous System Agonist and Antagonist Actions at Receptors Interference with Synthesis of the Transmitter Interference with Degradation of the Transmitter Interference with Storage and Release of the Transmitter …… Section 3 Drugs Affecting Central Nerv0us System Section 4 Cardiovascular Pharmacology Section 5 Inflammation，Immunomoudlation and Autacoid Pharmacology Section 6 Endocrine Drugs Section 7 Drugs Affecting Other Systems Section 8 Chemotherapeutic Drugs Index
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