序 前言 第一章 院士論壇 1 在福建中西醫(yī)結(jié)合研究院成立大會上的致辭 2 提倡多元模式推進(jìn)中西醫(yī)結(jié)合發(fā)展中醫(yī)藥事業(yè)——理念決定方法方法決定結(jié)果 3 雜談怎樣做一名合格的研究生導(dǎo)師 4 素食與心血管健康 5 關(guān)于活血化瘀臨床研究的心路歷程 6 用現(xiàn)代科學(xué)觀看中醫(yī) 7 當(dāng)前我國的科研道德建設(shè) 8 新世紀(jì)的藥物研究的趨勢與實(shí)踐 9 中醫(yī)藥在當(dāng)代的作用與使命 10 新藥創(chuàng)制:從大國走向強(qiáng)國 11 中醫(yī)藥送給世界的禮物——從屠呦呦教授獲得諾貝爾獎(jiǎng)?wù)f起 12 深入貫徹落實(shí)科學(xué)發(fā)展觀推動(dòng)中藥事業(yè)健康發(fā)展 13 Neuroprotective strategy協(xié)pharmaco-therapy 0f neurodeger'enative diseases 14 加強(qiáng)中醫(yī)藥自主創(chuàng)新提高防治疾病水平 15 中醫(yī)中藥在臨床腫瘤學(xué)中的作用 16 中藥資源的可持續(xù)發(fā)展 17 下丘腦-垂體-腎上腺軸在某些疾病中的重要作用 18 艾滋病的預(yù)防與控制 19 腫瘤防治路在何方——探索中醫(yī)的相關(guān)戰(zhàn)略地位 20 再生醫(yī)學(xué)研究進(jìn)展 21 神經(jīng)調(diào)控為核心,轉(zhuǎn)化醫(yī)學(xué)為目標(biāo),開拓針刺療法新高潮 22 枸杞子與神經(jīng)保護(hù) 23 探索傳統(tǒng)中藥復(fù)方黃芩湯(PHY906)在癌癥患者化療和放射治療上的輔助治療 24 全國中藥資源普查試點(diǎn)工作 第二章 心血管病研究 1 Blood Stasis Syndrome and its treatment with activating blood circulation to remove blood stasis therapy 2 Complementary/alternative medicine in cardiovascular diseases 2013 3 Complex networks approach for analyzing the correlation of Traditional Chinese Medicine syndrome evolvement and cardiovascular events in patients with stable Coronary Heart Disease 4 Chronic aspirin via dose-dependent and selective inhibition of cardiac proteasome possibly contributed a potential risk to the ischemic heart 5 Qualitative and quantitative analysis of the major constituents in Shexiang Tongxin Dropping Pill by HPLC- Q-TOF-MS/MS and UPLC-QqQ-MS/MS 6 Xiongshao capsule promotes angiogenesis of HUVEC via enhancing cell proliferation and up-regulating the expression ofbFGF and VEGF 7 The effect of Xuefu Zhuyu Decoction on in vitro endothelial progenitor cell tube formation 8 A microarray analysis of angiogenesis modulation effect of Xuefu Zhuyu Decoction on endothelial cells 9 In vitro angiogenesis effect of Xuefu Zhuyu Decoction and vascular endothelial growth factor., a comparison study 10 Effect of EphB4/EphrinB2 reverse signal on angiogenesis induced by Xuefu Zhuyu capsule containing serum in human microvascular endothelial cell 1 第三章 腫瘤研究 1 The applied research on serum protein fingerprints in the prediction of Qi Deficiency and Blood Stasis-Phlegm Syndrome with non-small cell lung cancer 2 Ethyl acetate extract from Jiedu Xiaozheng Yin inhibits proliferation of human hepatocellular carcinoma cells by suppressing polycomb gene product Bmil and Wnt/β-catenin signaling 3 Fuzheng-Yiliu granules inhibit growth ofhepatocellular cancer by regulating immune fuction and inducing apoptosis in vivo and in vitro 4 Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways 5 Pien Tze Huang-induced apoptosis in human colon cancer HT-29 cells is associated with regulation of the Bcl-2 family and activation of caspase 3 6 Pien Tze Huang inhibits tumor cell proliferation and promotes apoptosis via suppressing the STAT3 pathway in a colorectal cancer mouse model 7 Pien Tze Huang inhibits metastasis of human colorectal carcinoma cells via modulation of TGF-β/ZEB/miR-200 signaling network 8 Effects of Pien Tze Huang on angiogenesis in vivo and in vitro 9 Hedyotis Diffusa Willd extract induces apoptosis via activation of the mitochondrion- dependent pathway in human colon carcinoma cells 10 Scutellaria barbata D. Don inhibits tumor angiogenesis via suppression of Hedgehog pathway in a mouse model of colorectal cancer 第四章 骨關(guān)節(jié)炎研究 1 A biomechanical experiment and clinical study of figure of eight plus circular wiring fixation to treat olecranon fractures 2 Duhuo Jisheng Decoction promotes chondrocyte proliferation through accelerated G1/S transition in osteoarthritis 3 Computational approaches for exploring the potential synergy and polypharmacology of Duhuo Jisheng Decoction in the therapy of osteoarthritis 4 Duhuo Jisheng Decoction-containing serum promotes proliferation of interl eukin- 1β induced chondrocytes through the p 16 cyclin D 1 / CDK4 Rb pathway 5 Protective effects of the Tougu Xiaotong capsule on morphology and osteoprotegerin/nuclear factor-r,B ligand expression in rabbits with knee osteoarthritis 6 Experimental study of millimeter wave-induced differentiation of bone marrow mesenchymal stem cells into chondrocytes 7 Millimeter wave treatment inhibits apoptosis of chondrocytes via regulation dynamic equilibrium of intracellular free Ca2+ 8 Electroacupuncture promoted chondrocytes proliferation via accelerating G1/S transition in cell cycle 9 Deciphering the underlying mechanisms of DieSun Miaofang in traumatic injury from a systems pharmacology perspective 10 Replacing Shox2 with human SHOXleads to congenital disc degeneration of the temporomandibular joint in mice 第五章 中藥藥物物質(zhì)基礎(chǔ)研究 1 Bio-inspired sensor coupled with bio-bar code and hybridization chain reaction for Hg2+ assay 2 Solid phase extraction-field amplified sample injection coupled with CE-ESI-MS for on-line pre-concentration and quantitative analysis of brain-gut peptides 3 Enzyme-free and Label-free electrochemical biosensor for lead ion based on DNA concatamers and hexaammineruthenium 4 CE-ESI-MS coupled with dynamic pH junction online concentration for analysis of bioactive peptides in human urine samples 5 Field-amplified sample stacking in capillary electrophoresis for the determination of alkaloids in Sinomenium acutum 6 Antioxidant activity of polysaccharide extracted from Ganoderma lucidum using response surface methodology 7 Chemical composition, antimicrobial activity against Staphylococcus aureus and a pro-apoptotic effect in SGC-7901 of the essential oil from Toona sinensis (A.Juss.) Roem. leaves 8 Quantitative and chemical fingerprint analysis for the quality evaluation ofReceptaculum Nelumbinis by RP-HPLC coupled with hierarchical clustering analysis 9 Investigation of the extracts from Bidens pilosa Linn. vat. radiata Sch. Bip.for antioxidant activities and cytotoxicity against human tumor cells 10 Computational pharmacological comparison of Salvia miltiorrhiza and Panax notoginseng used in the therapy of cardiovascular diseases