About the Author Preface Acknowledgments PART Ⅰ Introduction CHAPTER 1 A Brief History CHAPTER 2 The Molecular Nature of Genes CHAPTER 3 An Introduction to Gene Function PART Ⅱ Methods of Molecular Biology CHAPTER 4 Molecular Cloning Methods CHAPTER 5 Molecular Tools for Studying Genes and Gene Activity PARTⅢ Transcription in Prokaryotes CHAPTER 6 The Mechanism of Transcription in Prokaryotes CHAPTER 7 Operons: Fine Control of Prokaryotic Transcription CHAPTER 8 Major Shifts in Prokaryotic Tran- scription CHAPTER 9 DNA-Protein Interactions in Pro- karyotes PARTⅣ Transcription in Eukaryotes CHAPTER 10 Eukaryotic RNA Polymerases and Their Promoters CHAPTER 11 General Transcription Factors in Eukarvotes CHAPTER 12 Transcription Activators in En- karyotes CHAPTER 13 Chromatin Structure and Its Effects on Transcription PARTY Ⅴ Posttranscriptional Events CHAPIER 14 Messenger RNA Processing I:Splicing CHAPTER 15 Messenger RNA Processing II. Cap- ping and Polyadenylation CHAPTER 16 Other RNA Processing Events PART Ⅵ Translation CHAPTER 17 The Mechanism of Translation Ⅰ: In- itiation CHAPTER 18 The Mechanism of Translation Ⅱ: Elongation and Termination CHAPTER 19 Ribosomes and Transfer RNA PART Ⅶ DNA Replication, Recombination, and Transposition CHAPTER 20 DNA Replication Ⅰ: Basic Mecha- nism and Enzymology CHAPTER 21 DNA Replication Ⅱ: Detailed Mechanism CHAPTER 22 Homologous Recombination CHAPTER 23 Transposition PARTⅧ Genomes CHAPTER 24 Genomics and Proteomics Glossary