《毒理學(xué)百科:精選卷(導(dǎo)讀版)》為毒理學(xué)醫(yī)學(xué)類(lèi)百科全書(shū),主要包含了毒理學(xué)的重要概念,如計(jì)量效應(yīng)、作用機(jī)制、試驗(yàn)程序、靶位等,還收集了與毒理學(xué)相關(guān)的歷史、法律、條例、數(shù)據(jù)庫(kù)。對(duì)毒理學(xué)家會(huì)相當(dāng)有用,同時(shí)也適用于醫(yī)學(xué)、法律、科學(xué)工作者查閱?!抖纠韺W(xué)百科:精選卷(導(dǎo)讀版)》是在原版Encyclopedia of Toxicology(2nd edn)的基礎(chǔ)上對(duì)詞條進(jìn)行的分類(lèi)重排。編成三卷,分別為精選卷、拓展卷與社科管理卷,更加適合國(guó)內(nèi)讀者閱讀。《毒理學(xué)百科:精選卷(導(dǎo)讀版)》涵蓋了毒理學(xué)研究的各個(gè)領(lǐng)域,從基礎(chǔ)到前沿,甚至一些尚存爭(zhēng)議的問(wèn)題也包含其中。第二版百科全書(shū)匯集了392作者提供的1057條目錄,而第一版只包括200名作者提供的749條目錄。實(shí)際上,第一版中所有條目的內(nèi)容在第二版中都得到了充實(shí),而某些條目則完全進(jìn)行了更新。在第二版中新出現(xiàn)的308個(gè)條目中,包括鳥(niǎo)類(lèi)生態(tài)毒理學(xué)、基準(zhǔn)劑量、殺蟲(chóng)劑、計(jì)算機(jī)毒理學(xué)、致癌效力因素、代謝組學(xué)、化學(xué)事件、蒙地卡羅分析、非致死性化學(xué)武器、無(wú)脊椎動(dòng)物生態(tài)毒理學(xué)、藥物濫用、癌癥化療因子和消費(fèi)產(chǎn)品等等。許多針對(duì)特殊化學(xué)物的條目都是全新的,而書(shū)中搜錄的國(guó)際組織也得到了很大的擴(kuò)展。某些條目羅列了許多著名的毒物中毒相關(guān)事件:如美國(guó)拉夫運(yùn)河事件、泰晤士海灘事件、切爾諾貝利事件和三里島事件等。另外許多條目涉及毒理學(xué)知識(shí)的社會(huì)應(yīng)用,如文化毒理學(xué)、環(huán)境犯罪、著名投毒者和中毒可件、古代化學(xué)生物戰(zhàn)以及美國(guó)環(huán)境運(yùn)動(dòng)歷史等。因此,新版的毒理學(xué)百科全書(shū)在長(zhǎng)度、廣度、以及深度上都對(duì)毒理學(xué)的許多方面進(jìn)行了更廣泛和深入的概述。
作者簡(jiǎn)介
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圖書(shū)目錄
Aberrations of Chromosomes(染色體畸變,染色體異常)see Chromosome Aberrations Absorption(吸收)Jules Brodeur and Robert Tardif Acceptable Daily Intake(ADI)(每日允許攝入量)Jaya Chilakapati and Harihara M Mehendale Aggregate Exposures(累積照射)Jeffrey H Driver Ames Test(埃姆斯試驗(yàn))Robin C Guy Analytical Toxicology(分析毒理學(xué))Shayne C Gad Aneuploidy(非整倍性)David A Eastrnond Animal Models(動(dòng)物模型)Shayne C Gad Aquatic Ecotoxicology(水域生態(tài)毒理學(xué)、水域生態(tài)毒物學(xué))see EcotoxicologyAquatic Aquatic Toxicity Testing(水生毒性試驗(yàn))see Toxicity Testing,Aquatic Avian Ecotoxicology(鳥(niǎo)類(lèi)生態(tài)毒理學(xué))see Ecotoxicology,Avian Behavioral Toxicity Testing(行為中毒試驗(yàn)、行為毒性試驗(yàn))see Toxicity Testing Behavioral Behavioral Toxicology(行為毒理學(xué))Deborah A Cory-Slechta Benchmark Dose(基準(zhǔn)劑量)Qiyu Jay Zhao Biological Exposure Index(生物照射)Alan J Weinrich Biomarkers,Environmental(環(huán)境生物標(biāo)記),Lee R Shugart Biomarkers,Human Health(人類(lèi)健康生物標(biāo)記)Rogene F Henderson Biotrans{ormation(生物轉(zhuǎn)化)Tanya C McCarthy and Christopher J Sinai Carcinogen-DNA Adduct Formation and DNA Repair(致癌原一DNA加合物形成與DNA修復(fù))Ainsley Weston andMiriam C Poirier Carcinogenesis(致癌作用)David E Malarkey and Robert R Maronpot Carcinogenicity Toxicity Testing(致癌毒性試驗(yàn))see Toxicity Testing Carcinog-enesis Chemical-Specific Adjustment Factor(CSAF)(化學(xué)特異性調(diào)節(jié)因子)Bette Meek Chromosome Aberrations(染色體畸變、染色體異常)Antone L Brooks Combustion Toxicology(燃燒毒理學(xué))Barbara C Levin and Erica D Kul igowski Common Mechanism of Toxicity(主要毒性機(jī)理)Beth Mileson Computational Toxicology(計(jì)算機(jī)毒理學(xué))S Satheesh Anand and Harihara M Meh-endale Cumulative Risk Assessment(累積危險(xiǎn)評(píng)價(jià))Jeffrey H Driver Deoxyribonucleic Acid(脫氧核糖核酸)see Aneuploidy;Carcinogen-DNA AdductFormation and DNA Repair;Chromosome Aberrations;DNA Phosphoramidites;Genetic Toxicology;Genomics.Toxicogenomics Dernlal Toxicity Testing(皮膚毒性試驗(yàn))see Toxicity Testing,Dermal Development Toxicity Testing(發(fā)育毒性試驗(yàn))see Toxicity Testing,Developmental Developmental Toxicology(發(fā)育毒理學(xué))Calvin C Willhite and Philip E Mirkes DNA(脫氧核糖核酸)see Aneuploidy;Carcinogen-DNA Adduct Formation and DNA Repair;Chromosome Aberrations;DNA Phosphoramidites;Genetic To- xicology;Genonlics,Toxicogenomics;Molecular Toxicology~Recombinant DNA Technology Toxicity Testing.Mutagenicity DNA Adduct(DNA加合物)see Carcinogen-DNA Adduct Formation and DNA Repair DNA Phosphoramidites(DNA亞磷酰胺)Sang-Tae Kim DNA Repair(DNA修復(fù))see Carcinogen-DNA Adduct Formation and DNA Repair Dominant Lethal Tests(顯性致死試驗(yàn))Samantha E Gad Dose-Response Relationship(劑量效應(yīng)關(guān)系)Samantha E Gad Ecotoxicology(生態(tài)毒理學(xué)、生態(tài)毒物學(xué))Chris Theodorakis Ecotoxicology,Aquatic(水域生態(tài)毒理學(xué))Yuan Zhao and Michael C Newman Ecotoxicology,Avian(-g類(lèi)生態(tài)毒理學(xué))Pierre Mineau1 Ecotoxicology,Genetic(遺傳生態(tài)毒理學(xué))Wendy L Rose and Susan L Anderson Ecotoxicology,Invertebrate(無(wú)脊椎動(dòng)物生態(tài)毒理學(xué))Pawel J Migula Ecotoxicology,Terrestrial(陸地生物生態(tài)毒理學(xué))Anne Fairbrother and Bruce Hope Ecotoxicology,Wildlife(野生動(dòng)植物生態(tài)毒理學(xué))Richard S Halbrook Environmental Hormone Disruptors(環(huán)境激素破壞劑)Lorenz Rhomberg and MaraSeeley Environmental Toxicology(環(huán)境毒理學(xué))Chris Theodorakis Exposure(暴露)Gary Whitmyre and Sam Kacew Exposure Assessment[(危害)暴露評(píng)估]Gary Whitmyre and Jeffrey H Driver Exposure Criteria(暴露標(biāo)準(zhǔn))Andrew Maier Eye Irritancy Testing(眼球刺激試驗(yàn))Samantha E Gad Food Safety and Toxicology(食品安全與毒理學(xué))Michael Bolger and Clark D Carr_ington Foreign Body Response(異物反應(yīng))Shayne C Gad Forensic Toxicology(法醫(yī)毒理學(xué))Felix K Adatsi Genetic Ecotoxicology(遺傳生態(tài)毒理學(xué))see Eeotoxicology,Genetic Genetic Toxicology(遺傳毒理學(xué))Joseph R Landolph Genomics,Toxicogenomics(基因組、毒物基因組)Kartik Shankar and Harihara M Mehendale GOOd Clinical Practice(GcP)(藥物臨床試驗(yàn)管理規(guī)范)Sharmilee P Sawant and Harihara M Mehendale Good LaboratorY Practices(GLP)(良好實(shí)驗(yàn)室管理規(guī)范)Robin C Guy Hormesis(毒物刺激作用)Elyisha A Hanniman and Christopher J Sinai Hormone Disruptors(激素破壞劑)see Environmental Hormone Disruptors Host-Mediated Assay(宿主間介試驗(yàn))David A Eastmond Hypersensitivity,Delayed Type(遲發(fā)型超敏反應(yīng))Leigh Ann Burns-Naas Immediately Dangerous to Life or Health(IDLH)Values(即刻性損傷或致死濃度) Alan J Weinrich Inhalation Testing(吸入試驗(yàn))see Toxicity Testing,Inhalation Interactions(相互作用)see Interactive Toxicity Interactive Toxicity(相互作用毒性)S Satheesh Anand and Harihara M Mehendale Irritation Testing(刺激試驗(yàn))see Toxicity Testing,Irritation LD50/LCs0(Lethal Dosage 50/Lethal Concentration 50)(半數(shù)致死劑量)Shayne C Gad Lethal,Dosage Or Concentration(致死劑量/濃度)see LD50/LC50(Lethal Dosage 50/Lethal Concentration 50) Levels of Effect in Toxicological Assessment(毒物效應(yīng)評(píng)價(jià)水平)Michael Dourson Lowest-Observed~Adverse-Effect Level(觀察到副作用的最小劑量)see Levels of Effect in Toxicological Assessment Lowest-Observed-Effect Level(觀察到作用的最小劑量,最低作用水平)see Leve- Is of Effect in Toxicological Assessment Margin of Exposure(MOE)(暴露界限)Udayan M Apte and Harihara M Mehendale Maximum Allowable Concentration(MAC)(最高容許濃度)Shayne C Gad Maximum T01erated Dose(MTD)(最大耐受劑量)Shayne C Gad Mechanisms of Toxicity(毒性機(jī)制)Sanjay Chanda and Harihara M Mehendale Mode of Action(作用方式)Lynne Haber Models(模型)see Animal Models Modifying Factors of Toxicity(毒性修飾因子)Frank C Lu and Sam Kacew M01ecular Toxic010gy_Recombinant DNA Technology(分子毒理學(xué)一重組DNA技術(shù)) Evan A Thackaberry Mouse Lymphoma Assay(小鼠淋巴瘤測(cè)定)Robin C Guy Neoplasia(瘤形成)see Carcinogenesis Neurotoxicity(神經(jīng)毒性)Peter S Spencer and Pamela J Lein Nonionizing Radiation(非電離輻射)see Radiation Toxicology,Ionizing and Non- ionizing No-Observed-Adverse-Effect Level(未觀察到的副作用水平)see Levels of Effect in Toxicological Assessment No-Observed-ElfeCt Level(未觀察到的效應(yīng)水平)see Levels of Effect in Toxicol- ogical Assessment Occupational Exposure Limits(職業(yè)性暴露極限)Andrew Maier Occupational Toxicology(職業(yè)毒理學(xué))Elizabeth V Wattenberg3 Ototoxicity(耳毒性)Michael J Sullivan PharmacokinetiCS/Toxicokinetics(藥物代謝動(dòng)力學(xué)/毒物代謝動(dòng)力學(xué))Robert Tardif and Jules Brodeur Pharmacology and Safety(安全藥理學(xué))see Safety Pharmacology(拓展卷) Radiation Toxicology,Ionizing and Nonionizing(電離輻射與非電離輻射毒理學(xué)) Bobby R Scott and Raymond A Guilmette Recombinant DNA(重組DNA)see Molecular Toxicology-Recombinant DNA Tee- hnology Safety Testing,Clinical Studies(臨床研究安全試驗(yàn))Alessandra Pagnoni366 Sensitivity Analysis(靈敏度分析)Virginia Lau Sensitization Testing(敏感試驗(yàn)、致敏試驗(yàn))see Toxicity Testing,Sensitization Short-Term Exposure Limit(短期暴露限度)see Occupational Exposure Limits Subchronic Toxicity(亞慢性毒性)see Toxicity,Subchronic Teratology(畸形學(xué))see Developmental Toxicology Teratology Testing(致畸實(shí)驗(yàn))see Toxicity Testing,Developmental Terrestrial Ecotoxicology(陸地生態(tài)毒理學(xué))see Ecotoxicology,Terrestrial Threshold Limit Value(閾限值)see Occupational Exposure Limits Toxicity Testing,Alternatives(選擇性毒性試驗(yàn))Shayne C Gad Toxicity Testing,Aquatic(水域毒性試驗(yàn))Shayne C Gad Toxicity Testing,Behavioral(行為毒性試驗(yàn))Samantha E Gad Toxicity Testing,Carcinogenesis(致癌毒性試驗(yàn))Shayne O Gad Toxicity Testing,Dermal(皮膚毒性試驗(yàn))Samantha E Gad and Shayne C Gad Toxicity Testing,Developmental(發(fā)育毒性試驗(yàn))Rochelle W Tyl Toxicity Testing,Inhalation(吸人毒性試驗(yàn))Samantha E Gad and Shayne C Gad Toxicity Testing,Irritation(刺激毒性試驗(yàn))Pertti J Hakkinen Toxicity Testing,Modeling(模型化毒性試驗(yàn))Charles A Pittinger,Andrew Worth, Joanna Jaworska and Joanne Shatkin Toxicity Testing,Mutagenicity(致突變毒性試驗(yàn))Robin C Guy435 Toxicity Testing,'Read Across Analysis'[識(shí)讀交叉分析(毒性試驗(yàn))]Pertti J Hakkinen Toxicity Testing,Reproductive(生殖毒性試驗(yàn))Rochelle W Tyl Toxicity Testing,Sensitization(致敏毒性試驗(yàn))Rob in C Guy Toxicity Testing,Validation(毒性試驗(yàn)驗(yàn)證)Leon H Bruner,G J Carr,M Chamb- erlain and R D Curren Toxicity,Acute(急性毒性)Donald J Ecobichon Toxicity,Chronic(長(zhǎng)期毒性)Donald J Ecobichon Toxicity,Subchronic(亞慢性毒性)Donald J Ecobichon Toxicokinetics(毒物代謝動(dòng)力學(xué))see Pharmacokinetics/Toxicokinetics Toxicology(毒理學(xué))Gabriel L Plaa Toxicology,Intuitive(直覺(jué)毒理學(xué))Pertti J Hakkinen Uncertainty Analysis(不確定檢驗(yàn))Virginia Lau Uncertainty Factors(不確定系數(shù))Michael Dourson Validation of Toxicity Testing(毒性試驗(yàn)驗(yàn)證)see Toxicity Testing,Validation Veterinary Toxicology(獸醫(yī)毒理學(xué))Wilson K Rumbeiha and Frederick W Oehme Virtually Safe Dose(VSD)(實(shí)際安全劑量)Stephen M DiZio 拓展卷目錄 社科管理卷目錄 未收錄詞條