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蛋白質(zhì)芯片:英文本

蛋白質(zhì)芯片:英文本

定 價:¥65.00

作 者: (美)M.謝納著
出版社: 科學出版社
叢編項: 現(xiàn)代生物技術前沿
標 簽: 醫(yī)用生物學

ISBN: 9787030151834 出版時間: 2005-04-01 包裝: 平裝
開本: 26cm 頁數(shù): 488頁 字數(shù):  

內(nèi)容簡介

  人類基因組大規(guī)模測序工作已經(jīng)完成,隨著以功能基因組學和蛋白質(zhì)組學為主要研究內(nèi)容的后基因時代來臨,蛋白質(zhì)芯片作為檢測蛋白質(zhì)存在和運動變化的高效工具,將為本世紀的疾病診斷和治療、新藥開發(fā)、分子生物學、航空航天、司法鑒定、食品衛(wèi)生及環(huán)境監(jiān)測等領域帶來一場革命。生物芯片技術是一種高通量檢測技術,它包括基因芯片、蛋白質(zhì)芯片及芯片實驗三大領域。蛋白質(zhì)芯片以蛋白質(zhì)代替DNA作為檢測目的物,此基因芯片更接近生命活動的物質(zhì)層面,以直接測定蛋白質(zhì)的相對水平及與其他分子在交互作用情況,以定量化的方式反映基因的活動情況,因而蛋白質(zhì)芯片有著比基因芯片更加直接的應用前景?!兜鞍踪|(zhì)芯片(影印版)》對蛋白質(zhì)芯片技術進行了全面細致地闡述,包括技術原理、生產(chǎn)方法、表面化學、檢測策略以及抗原、抗體數(shù)據(jù)分析,同時全書圖文并茂,提供了許多生物學應用實例及實驗草案?!兜鞍踪|(zhì)芯片(影印版)》知識全面,內(nèi)容豐富,集合了蛋白質(zhì)芯片技術的基礎知識和前沿研究,實用性廣泛,可讀性強。適用于從事生物芯片研究開發(fā)以及生物信息學、蛋白質(zhì)組學、基因組學、分子生物學、生物化學、細胞生物學、生物技術等相關研究領域的教學科研人員或技術人員參考使用,也可做為研究生教材。

作者簡介

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圖書目錄

Table of Contents
List of Contributors
Preface
Foreword
Chapter 1
Principles of Protein Microarrays
Mark Schena
Chapter 2
Novel Strategies in Protein Microarray Generation and Detection
Yee-Peng Rina Lue, Su-Yin Dawn Yeo, Lay-Pheng Tan, Mahesh Uttamchandani, Grace Yi-Jun Cben, and Shao Q. Yao
Chapter 3
Practical Guide to Protein Microarrays: Assay Systems, Methods, and Algorithms
Mikhail Soloviev and Jon Terrett
Chapter 4
Microarrays for the High-Throughput Analysis of Protein-Carbohydrate Interactions
William G. T. Willats
Chapter 5
Protein Microarrays: Principles and Limitations
Victor N. Morozov
Chapter 6
System-Oriented Proteomics Using Protein-Domain Microarrays
Alexsandra Espejo and Mark T. Bedford
Chapter 7
Colorimetric Microarray Assays for Rheumatoid Arthritis using a Recombinant Proteome Library
Stewart J. Lebrun
Chapter 8
Academic and Commercial Aspects of Protein Microarray Development
Seung-yong Seong
Chapter 9
Analyzing Proteins and Protein Modifications with ArrayTubeTM Antibody Microarrays
Stefan W6lfl, Annegret Dummer, Larissa Pusch, Marina efalz, Lin Wan, Joachim H. Clement, lnes Leube, and Ralf Ehricht
Chapter 10
Non-Contact Dispensing for Protein Microarrays
Thomas C. Tisone and John L. Tonkinson
Chapter 11
High Speed, High Efficiency Protein Printing by BioLPTM
Bradley R. Ringeisen, Jason A. Barron, and David B. Krizman
Chapter 12
Putting the "BID" in Biochips: Capture Agents for Protein Microarray Expression Profiling Platforms
David S. Wilson, Michael L. Phelan, and Steffen Nock
Chapter 13
Protein Biochips for the Profiling of Allergen-Specific Antibodies
Christian Harwanegg, Susanne Spitzauer, Rudolf Valenta, Manfred W. Mueller, and Reinhard Hiller
Chapter 14
Solid Supports for Protein Microarrays and Related Devices
Wlad Kusnezow, Timo Pulli, Olaf Witt, and J6rg D. Hoheisel
Chapter 15
Protein Microarrays for Biosensor Applications
Michael G. Weller
Chapter 16
Technological Aspects of Protein Microarrays and Nanoarrays
Fan-Gang Tseng, Shih-Chang Lin, Da-Jen Yao, Haimei Huang, and Ching-Chang Chieng
Chapter 17
Mega-Dense Nanoarrays: The Challenge of Novel Antibody Microarray Formats
Christer Wingren, Lars Montelius, and CarlA. K. Borrebaeck
Chapter 18
INFINITITM System: An Automated Multiplexing Protein Microarray Platform
Anupam Talapatra, Vijay Mahant, Ram Vairavan, Fareed Kureshy, and Gary Hardiman
Chapter 19
Protein Microarrays for Analysis of Antibody Responses in Animals and Humans
Paul J. Utz, Lawrence Steinman, and William H. Robinson
Chapter 20
G-Protein Coupled Receptor Microarrays: A Versatile Tool fo Drug Discovery
Ye Fang, Yulong Hong, Jinlin Peng, and Joydeep Lahiri
Chapter 21
Proteome-Scale Analysis of the Immune Response Against Pathogenic Microorganisms
Tito Bacarese-Hamilton, Julian Gray, and Andrea Crisanti
Chapter 22
Development of Protein Microarrays for Drug Discovery...
Jens O. Koopmann, Michael B. McAndrew, and Jonathan M. Blackburn
Chapter 23
Development and Applications of Functional Protein Microarrays
James Ball, Barry Schweitzer, Paul Predki, and Michael Snyder
Chapter 24
Enabling Tools for Protein Microarrays
Todd Martinsky
IndexFFFF

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